Work with biodegradable polymers has also yielded polyorthoesters that are ph sensitive and that will degrade more quickly in acidic environments 3 such polymers have been studied as the central core of a drug delivery system in which the polymer insulin matrix is surrounded by a membrane containing grafted glucose oxidase which provides the reaction substrate and the change in ph necessary to enhance biodegradation and subsequent insulin delivery. Polymers for controlled drug delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms the book primarily discusses classes of polymers and polymeric vehicles including particulates such as latexes coacervates ion exchange resins and liposomes as well as non particulate vehicles such as enteric . Stimuli responsive polymers offer a drug delivery platform that can be utilised to deliver drugs at a controlled rate and in a stable and biologically active form over many decades interest in stimuli responsive polymers has increased and great deal of work has been committed to developing environmentally sensitive macromolecules that can be moulded into new smart polymers. 3 reviews polymers for controlled drug delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms the
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